Tributyl Citrate

Synonyms: Citric acid, tributyl ester; Citroflex 4; TBC; tri-n-butyl citrate; tributyl 2-hydroxy-1,2,3-propanetricarboxylate.

Description: Tributyl citrate is a clear, odorless, practically colorless, oily liquid.

Chemical Name: 1,2,3-Propanetricarboxylic acid, 2-hydroxy, tributyl ester

Plasticizer

• Tributyl citrate is used to plasticize polymers in formulated pharmaceutical coatings.

• The coating applications include capsules, tablets, beads, and granules for taste masking, immediate release, sustained-release, and enteric formulations.

Tributyl citrate is incompatible with strong alkalis and oxidizing materials.

Tributyl citrate is used in oral pharmaceutical formulations. It is generally regarded as an essentially nontoxic and nonirritating material. However, ingestion of large quantities may be harmful.

Observe normal precautions appropriate to the circumstances and quantity of material handled. Tributyl citrate may be irritating to the eyes. It may also be irritating to the respiratory system at elevated temperatures. Gloves and eye protection are recommended for normal handling, and a respirator is recommended for elevated temperatures.

Acetyltributyl citrate; acetyltriethyl citrate; triethyl citrate.