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Sodium Sulfacetamide/​Sulfur

    Brands

    DEA Class; Rx

    Common Brand Names; Sulfacet R, Prascion Cleanser, Avar, Avar LS, Avar-E, Avar-E LS, Cerisa Wash, Clarifoam EF, Claris Clarifying Wash, Clenia Foaming Wash, Clenia Emollient Cream, Prascion FC Facial Cleansing Cloths, Prascion RA with Sunscreens, Rosaderm Cleanser, Rosanil Cleanser, Sumadan Wash, Sumaxan Cleansing Pads, Sumaxin TS, Sumaxin Wash, Zencia Wash, Rosula, Rosula Wash

    • Acne Agents, Topical Combos; 
    • Antipsoriatics, Topical; 
    • Antiseborrheic Agents, Topical

    Combination of an sulfonamide antimicrobial (sulfacetamide) and an antimicrobial and keratolytic agent (sulfur)
    Used to treat acne rosacea, acne vulgaris, and seborrheic dermatitis
    Widespread historical use in dermatology, but not formally evaluated by the FDA for clinical efficacy or safety.

    Indicated in the topical control of acne vulgaris and rosacea

    For the adjunctive treatment of acne vulgaris, acne rosacea, and seborrheic dermatitis.

    Hypersensitivity to sulfa drugs

    • Local irritation
    • Pruritus
    • Erythema
    • Itching
    • Edema

    External use only

    Avoid contact with eyes or mucous membranes

    Avoid UV exposure

    Discontinue if excessive skin irritation develops

    Severe reactions including Stevens-Johnson syndrome, toxic epidermal necrolysis, fulminant hepatic necrosis, agranulocytosis, aplastic anemia, and other blood dyscrasias reported

    Pregnancy Category: C

    Lactation: Unknown whether excreted in breast milk, use caution

    Adults

    3 applications/day for creams, gels, lotions, and foam; 2 applications/day for washes and cleansers.

    Geriatric

    3 applications/day for creams, gels, lotions, and foam; 2 applications/day for washes and cleansers.

    Adolescents

    3 applications/day for creams, gels, lotions, and foam; 2 applications/day for washes and cleansers.

    Children

    >= 12 years: 3 applications/day for creams, gels, lotions, and foam; 2 applications/day for washes and cleansers.
    < 12 years: Safety and efficacy have not been established.

    Infants

    Safety and efficacy have not been established.

    Neonates

    Safety and efficacy have not been established.

    sodium sulfacetamide/sulfur

    topical cream

    • 10%/2% (Avar-E LS)
    • 10%/5% (Clenia Emollient Cream, Avar-E)

    topical cream with sunscreen

    • 10%/5% (Prascion RA with Sunscreens)

    topical foam

    • 10%/5% (Clarifoam EF)

    cleanser

    • 8%/4% (Sumaxin TS)
    • 9%/4% (Sumaxin Wash, Zencia Wash)
    • 9%/4.5% (Sumadan Wash)
    • 10%/1% (Cerisa Wash)
    • 10%/2% (Avar LS)
    • 10%/4% (Claris Clarifying Wash, Sumaxin Cleansing Pads)
    • 10%/4.5% (Rosula Wash)
    • 10%/5% (Prascion Cleanser, Prascion FC Facial Cleansing Cloths, Rosaderm Cleanser, Rosanil Cleanser, Clenia Foaming Wash, Avar)

    Cleansing Cloth

    • 10%/5% (Rosula)