Sodium Formaldehyde Sulfoxylate

Synonyms: Formaldehyde hydrosulfite; formaldehyde sodium sulfoxylate; formaldehydesulfoxylic acid sodium salt; methanesulfinic acid, hydroxy-, monosodium salt; monosodium hydroxymethane sulfinate; Rongalite; sodium hydroxymethane sulfinate; sodium hydroxymethylsulfinate; sodium methanalsulfoxylate; sodium sulfinomethanolate.

Description: When freshly prepared, sodium formaldehyde sulfoxylate occurs as white, odorless crystals, which quickly develop a characteristic garlic odor on standing.

Chemical Name: Sodium formaldehyde sulfoxylate

Sodium formaldehyde sulfoxylate dihydrate

Antioxidant.

• Sodium formaldehyde sulfoxylate is a water-soluble antioxidant and is generally used as the dihydrate.

• It is used in the formulation of injection products at a level of up to 0.1% w/v in the final preparation administered to the patient.

Sodium formaldehyde sulfoxylate is incompatible with strong oxidizing agents; it is decomposed by dilute acid.

The toxicological properties of sodium formaldehyde sulfoxylate have not been fully investigated. However, it is used in the formulation of injection products at a level to 0.1% w/v in the final preparation administered to the patient. Sodium formaldehyde sulfoxylate is moderately toxic by ingestion, and when heated to decomposition it emits toxic fumes of sulfur dioxide and sodium oxide.

Observe normal precautions appropriate to the circumstances and quantity of the material handled. May cause irritation of the eyes, skin, respiratory tract and digestive tract; the use of eye protection, a respirator and gloves is strongly recommended.

Zinc formaldehyde sulfoxylate.