General Description
Synonyms: Aceite de alazor; aceite de cartamo; carthami oleum raffinatum; dygminu aliejus, rafinuotas; huile de carthame; safflorolja, raffinerad; safflower oil (unhydrogenated); saflonoljy puhdistettu.
Description: Refined safflower oil is a clear, viscous, yellow to pale-yellow liquid, with a slight vegetable odor.
Chemical Name: Safflower oil
Uses
Safflower oil is mainly used as an oleaginous vehicle in oral and topical formulations.
It is also used as a component of parenteral fat emulsions for the preparation of parenteral nutrition solutions.
Safflower oil has been used as a vehicle in the development of an oral dosage form containing a novel viral-specific inhibitor of the replication of human rhinoviruses.
It has also been used as a solvent for a capsule formulation containing a new antilipemic agent; formulations containing safflower oil were found to have the greatest bioavailability in dogs compared with formulations containing PEG 300 or water.
A topical lotion containing 3% safflower oil is commercially available, and parenteral fat emulsions containing a mixture of safflower oil 5% and soya oil 5%, or 10% and 10%, respectively, have been administered as part of total parenteral nutrition regimes.
Safflower oil is used as a food, being consumed in the form of soft margarine, salad oils, and cooking oils. It is also used in cosmetics products such as soaps, lotions, creams, and hair-care preparations.
Incompatibilities
Safflower oil is incompatible with strong oxidizing agents.
Safety
Safflower oil is an edible oil and generally presents no significant health hazards following eye contact, skin contact, oral ingestion, or inhalation. Skin irritation or allergic reactions, or eye irritation may occur. Ingestion of large doses can cause vomiting. Safflower oil may cause diarrhea
Handling Precautions
Observe normal precautions appropriate to the circumstances and quantity of the material handled. When heated to decomposition, safflower oil emits acrid smoke and irritating fumes.
Related Substances
Almond oil; canola oil; corn oil; cottonseed oil; peanut oil; safflower glycerides; sesame oil; soybean oil; sunflower oil.