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    DAE Class; Rx

    Common Brand Names; RULID

    • Macrolides

    Roxithromycin is a macrolide with antibacterial properties similar to that of Erythromycin. Roxithromycin is active against gram positive bacteria for example, staphylococci, streptococci, listeria, corynebacteria; gram negative bacteria for example gonococci, Hemophilus influenza, Hemophilus ducreyi, Legionella, and atypical pathogen, for example mycoplasma and chlamydia. Roxithromycin is well torelated by children and adults. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular interval of time throughout the day and night as prescribed. Roxithromycin is important to take the drug for the full time period as prescribed, discontinuation of the drug may result in ineffective treatment.

    Roxithromycin is primarily indicated in conditions like Ent infections, Genitourinary tract infections, Pneumonia, Skin infections.

    Roxithromycin is contraindicated in conditions like Hepatic disease, Hypersensitivity.

    The symptomatic adverse reactions produced by Roxithromycin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Weakness, Dizziness, Headache, Diarrhea, Rashes, Nausea and vomiting, Elevated alkaline phosphatase, Epigastric pain, GI disturbance, Elevated SGPT & SGOT.

    Precaution should be taken in hepatic insufficiency, prenancy and lactation. It should be used with caution in patients with any allergy, especially to antibiotics. Take appropriate measures if secondary infection occurs.

    Drug should not be given to patients suffering from Kidney dysfunction.

    Acute bronchitis, Acute exacerbations of chronic bronchitis, Acute pharyngitis, Community-acquired pneumonia, Nongonococcal urethritis, Sinusitis, Skin and soft tissue infections, Tonsillitis

    Adult: Recommended dose: 150 mg bid or 300 mg once daily for 5-10 days. Duration of treatment may be longer depending on the indication and clinical response.
    Child: 6-40 kg: 5-8 mg/kg daily given in 2 divided doses; ≥40 kg: 150 mg bid. Usual treatment duration: 5-10 days. Duration of treatment must not exceed 10 days.


    Susp: 50 mg/5ml,
    Tabs: 50 mg, 100 mg, 150 mg, 300 mg,
    Caps: 150 mg, 300 mg,