Skip to content

Roxatidine

    Brands

    Roxatidine

    DAE Class; Rx

    Common Brand Names; ROXANE

    • Anti-peptic ulcerants

    Roxatidine used in the management of peptic ulcer disease.

    Roxatidine is primarily indicated in conditions like GI ulceration, Hyperacidity, and can also be given in adjunctive therapy as an alternative drug of choice in Reflux oesophagitis.

    Roxatidine is contraindicated in conditions like Anuria.

    The symptomatic adverse reactions produced by Roxatidine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Headache, Diarrhea, Restlessness, Constipation, Skin rashes, Nausea and vomiting.

    Roxitadine should be used with caution in patients with impaired kidney or liver function. Intravenous injection should be given slowly and intravenous infusion is recommended in patients with cardiovascular impairment.

    Drug should not be given to patients suffering from Kidney dysfunction.

    –

    Intravenous
    Upper gastrointestinal haemorrhage

    Adult: 75 mg bid via slow inj or infusion.


    Oral
    Zollinger-Ellison syndrome

    Adult: 75 mg bid.


    Oral
    Gastro-oesophageal reflux disease

    Adult: 75 mg bid or 150 mg at bedtime for 6-8 wk.


    Oral
    Premedication before anaesthesia

    Adult: 75 mg in the evening on the day before surgery and repeated 2 hr before induction of anaesthesia. Alternatively, 150 mg once on the night before surgery.


    Oral
    Peptic ulcer

    Adult: 150 mg at bedtime or 75 mg bid daily for 4-6 wk. Maintenance: 75 mg at bedtime.


    Oral
    Gastritis

    Adult: 75 mg once daily in the evening.

    Roxatidine

    Tabs: 75 mg, 150 mg