Polacrilin Potassium

Synonyms: Amberlite IRP-88; methacrylic acid polymer with divinylbenzene, potassium salt; polacrilinum kalii.

Description: Polacrilin potassium occurs as a cream-colored, odorless and tasteless, free-flowing powder. Aqueous dispersions have a bitter taste.

Chemical Name: 2-Methyl-2-propenoic acid polymer with divinylbenzene, potassium salt

Antimicrobial preservative.

• Polacrilin potassium is a cation-exchange resin used in oral pharmaceutical formulations as a tablet disintegrant.

• ConcenP 504 Polacrilin Potassium trations of 2–10% w/w have been used for this purpose, although 2% w/w of polacrilin potassium is usually sufficient.

• Other polacrilin ion-exchange resins have been used as excipients to stabilize drugs, to mask or modify the taste of drugs, and in the preparation of sustained-release dosage forms and drug carriers.

• Polacrilin resins are also used in the analysis and manufacture of pharmaceuticals and food products.

Incompatible with strong oxidizing agents, amines, particularly tertiary amines, and some other substances that interact with polacrilin resins.

Polacrilin potassium and other polacrilin resins are used in oral pharmaceutical formulations and are generally regarded as nontoxic and nonirritant materials. However, excessive ingestion of polacrilin resins may disturb the electrolyte balance of the body

Observe normal precautions appropriate to the circumstances and quantity of material handled. Polacrilin potassium may be irritating to the eyes; eye protection and gloves are recommended

Polacrilin.