Pefloxacin

Pefloxacin

DAE Class; Rx

Common Brand Names; PEFLACINE

• Quinolones

Pefloxacin is a fluoroquinolone antibiotic with actions and uses similar to those of ciprofloxacin. Pefloxacin is used to treat a variety of bacterial infections like respiratory tract, ENT, skin, urinary tract infections etc. Antibiotics require constant drug level in body for therapeutic effect. This is achieved by taking the drug at regular intervals of time throughout the day and night as prescribed. Pefloxacin is important to take the drug for the full time period as prescribed. Discontinuation of the drug, may result in ineffective treatment.

Pefloxacin is primarily indicated in conditions like Acne, Bacterial infections, Bronchitis, Burns, Conjuctivitis, Cystitis, Dysenteries, Folliculitis, Impetigo, Otitis media, Pneumonia, Prostatitis, Pyelonephritis, Respiratory tract infections, Sedation in intensive care, Sinusitis, Superficial infections, Surgical infections, Tonsillitis, Urethritis.

Pefloxacin is contraindicated in conditions like Hypersensitivity.

The symptomatic adverse reactions produced by Pefloxacin are more or less tolerable and if they become severe, they can be treated symptomatically, these include Headache, Insomnia, GI upset, Muscle pain, Articular pain.

Adjust doses in the renal and hepatic impairment. Ask patients to report any signs of depression.

Drug should not be given to Paediatrics, and Pregnant Mothers.

Oral
Susceptible infections
Adult: 400 mg bid.
Renal impairment: Dose reduction may be necessary.

Oral
Acute uncomplicated cystitis in women
Adult: 800 mg as single dose.
Renal impairment: Dose reduction may be necessary.

Oral
Gonococcal urethritis in men
Adult: 800 mg as single dose.
Renal impairment: Dose reduction may be necessary.

Pefloxacin