General Description
Synonyms: Alcohol oleicus; HD-Eutanol V PH; Novol; Ocenol; cis-9- octadecen-1-ol; oleic alcohol; oleo alcohol; oleol.
Description: Oleyl alcohol occurs as a pale yellow oily liquid that gives off acrid fumes when heated
Chemical Name: (Z)-9-Octadecen-1-ol
Functions
Antifoaming agent; dissolution enhancer; emollient; emulsifying agent; skin penetrant; sustained-release agent.
Uses
Oleyl alcohol is mainly used in topical pharmaceutical formulations and has been used in transdermal delivery formulations.
It has been utilized in the development of biodegradable injectable thermoplastic oligomers, and in aerosol formulations of insulin and albuterol.
Therapeutically, it has been suggested that oleyl alcohol may exhibit antitumor properties via transmembrane permeation.
Safety
Oleyl alcohol is mainly used in topical pharmaceutical formulations and is generally regarded as a nontoxic and nonirritant material at the levels employed as an excipient. However, contact dermatitis due to oleyl alcohol has been reported.
Handling Precautions
Observe normal precautions appropriate to the circumstances and quantity of material handled.
Related Substances
Oleic acid; oleyl oleate.