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Neomycin/Polymyxin B/Hydrocortisone/Bacitracin

    Brands

    DEA Class; Rx

    Common Brand Names; Neo-Polycin HC

    • Corticosteroids, Ophthalmic

    Bacitracin/hydrocortisone/neomycin/polymyxin topical (OTC)

    Brand and Other Names: Cortisporin Ointment
    • Classes: Corticosteroids, Topical; 
    • Topical Antimicrobials

    Topical combination product containing steroid and antibacterial/antifungal agent
    Used for the treatment of skin infections

    Indicated for the treatment of corticosteroid-responsive inflammatory ocular conditions where a bacterial ophthalmic infection or a risk of bacterial ophthalmic infection exists (e.g., inflammation of palpebral and bulbar conjunctiva, cornea and anterior segment of the globe where the inherent risk of corticosteroid use in bacterial conjunctivitis is accepted to obtain a decrease in edema and inflammation; also in chronic anterior uveitis and corneal injury from chemical, radiation, or thermal burns, or penetration of foreign objects).

    For the treatment of corticosteroid-responsive dermatoses with secondary infection.

    Hypersensivity to neomycin

    Glaucoma

    Viral diseases of cornea and conjunctiva (epithelial herpes simplex keratitis, vaccinia, varicella)

    Mycobacterial infection of eye & fungal diseases of ocular structures

    Hypersensitivity

    • Allergies
    • Glaucoma
    • Rash
    • Superinfection (herpes)
    • Skin sensitization
    • Burning
    • Itching
    • Irritation
    • Dryness
    • Folliculitis
    • Hypertrichosis
    • Acneiform eruptions
    • Hypopigmentation
    • Perioral dermatitis
    • Allergic contact dermatitis
    • Maceration of the skin
    • Secondary infection
    • Skin atrophy
    • Striae
    • Miliaria

    Not used much, because of hypersensitivity reactions to neomycin; also, because of steroid component, adequate follow up is essential

    Prolonged use or misuse of ocular corticosteroid may result in glaucoma, superinfection (herpes) etc

    Newer agents have better steroid & antibiotic coverage

    For external use only

    Pregnancy Category: C

    Lacation: Unknown

    Adults

    8 g or 10 days for ophthalmic ointment then reevaluate before further therapy; 4 applications/day for up to 7 days topically.

    Elderly

    8 g or 10 days for ophthalmic ointment then reevaluate before further therapy; 4 applications/day for up to 7 days topically.

    Adolescents

    Safety and efficacy have not been established.

    Children

    Safety and efficacy have not been established.

    Infants

    Safety and efficacy have not been established.

    Bacitracin ophthalmic/neomycin/polymyxin B/hydrocortisone

    ophthalmic ointment

    • 400units/0.35%/10,000units/1%

    Bacitracin/hydrocortisone/neomycin/polymyxin

    topical ointment

    • (400 units/10mg/35mg/4000 units)/1gram