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Neomycin/Polymyxin B/Gramicidin

    Brands

    DEA Class; Rx

    Common Brand Names; Gramicidin, Neosporin Ophthalmic Solution, Neocin-PG

    • Antibiotics, Ophthalmic Combos

    Aminoglycoside neomycin with polymyxin B and gramicidins A, B and C
    Ophthalmic preparation; used for ophthalmic bacterial infections
    Combination provides overlapping coverage against a wide range of gram-positive and gram-negative bacteria, including streptococci

    Indicted for the treatment of superficial ophthalmic infection, including bacterial conjunctivitis, keratitis, keratoconjunctivitis, blepharitis, and blepharoconjunctivitis.
    For ophthalmic surgical infection prophylaxis.

    Aminglycoside/neomycin hypersensitivity; hypersensitivity to any product component

    Hypersensitivity

    Itching, swelling, and conjunctival erythema

    Local transient irritation

    Vesicular and maculopapular dermatitis

    Angioneurotic edema

    Urticaria

    Watch for NEOMYCIN ocular sensitivity

    Defects in visual acuity may occur with prolonged use

    Posterior subpapular cataract formation, and secondary ocular infections reported with prolonged use

    Prolonged use may result in overgrowth of nonsusceptible organisms including fungi; if superinfection occurs, appropriate measures should be initiated

    Bacterial resistance to may develop; if purulent discharge, inflammation, or pain becomes aggravated, patient should discontinue use and consult a physician

    Allergic cross-reactions may occur which could prevent use of any or all of the following antibiotics for treatment of future infections: kanamycin, paromomycin, streptomycin, and possibly gentamicin

    Animal reproduction studies have not been conducted with neomycin sulfate, polymyxin B sulfate, or bacitracin

    Not known whether drug is excreted in human milk; because many drugs are excreted in human milk, exercise caution when drug is administered to a nursing woman

    Adults

    Maximum dosage information not available.

    Geriatric

    Maximum dosage information not available.

    Adolescents

    Maximum dosage information not available.

    Children

    Maximum dosage information not available; safety and efficacy have not been established.

    Infants

    Maximum dosage information not available; safety and efficacy have not been established.

    Neomycin/Polymyxin B/Gramicidin

    ophthalmic solution

    • (1.75 mg/10,000/0.025 mg)/1mL (10mL)