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Neomycin/Polymyxin B/ Bacitracin/Pramoxine

    DEA Class; OTC

    Common Brand Names; Neosporin Plus Pain Relief Ointment, TriBiozene Ointment

    • Antibacterials, Topical

    Neomycin, polymyxin B, and bacitracin elicit bacteriostatic activity

    Pramoxine provides local anesthetic effect

    Indicted for the treatment of Skin Infection Prevention

    Hypersensitivity

    Allergic contact dermatitis

    Ototoxicity and nephrotoxicity possible if treating large surface area or chronic use

    Pregnancy category: C

    Lactation: unknown if neomycin, polymyxin B, or bacitracin excreted in breast milk; systemic absorption of topical lidocaine has been reported

    Adults

    Apply small amount to cleansed wound 1-3 times/day; not to exceed 1week

    Pediatric

    Apply small amount to cleansed area 1-3 times/day; not to exceed 1week

    Neomycin/polymyxin B/bacitracin/pramoxine

    topical ointment

    • (3.5mg/10,000units/500units/10mg)/g