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Neomycin/Polymyxin B/ Bacitracin/Lidocaine

    DEA Class;  OTC

    Common Brand Names; Lanabiotic Ointment

    • Anesthetics, Topical; 

    Neomycin, polymyxin B, and bacitracin elicit bacteriostatic activity

    Lidocaine provides local anesthetic effect

    Indicated for Skin Infection Prevention


    Allergic contact dermatitis

    Ototoxicity and nephrotoxicity possible if treating large surface area or chronic use

    Lidocaine may be significantly absorbed from mucosal surfaces and open wounds

    Pregnancy category: C

    Lactation: unknown if neomycin, polymyxin B, or bacitracin excreted in breast milk; systemic absorption of topical lidocaine has been reported

    Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs


    Skin Disorders

    Apply q8-12hr

    Hemorrhoids, Anal fissures, Pruritus ani

    Apply BID to areas of discomfort and anal opening


    Safety and efficacy not established

    neomycin/polymyxin B/bacitracin/lidocaine

    topical ointment

    • (3.5mg/10,000units/500units/40mg)/g