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Nadroparin

    Brands

    DAE Class; Rx

    Common Brand Names; Fraxiparin[e], Fraxodi

    • Anticoagulants/Platelet deaggregators

    Nadroparin is an anticoagulant used to prevent the formation and growth of blood clots in patients with certain specific medical conditions. It is also used to prevent blood clots that may potentially form during certain medical procedures. It is used in combination with aspirin to prevent serious complications associated with angina and heart attacks.

     

    • Prophylaxis of ischemic complications in unstable angina
      This medicine is used to prevent the blockage of coronary arteries (major blood vessels carrying blood and oxygen to the heart) and associated complications. A blockage of the coronary artery may result in a heart attack, anginal pain, and heart rhythm abnormalities. This medicine is administered along with aspirin to prevent the complications.
    • Prophylaxis of venous thromboembolism during surgical procedures
      This medicine is used to prevent the formation of blood clots during major surgical procedures.
    • Venous thromboembolic events
      This medicine is used to treat and prevent the formation of blood clots in veins that could potentially break loose and migrate to larger veins in the legs or lungs, causing further complications.
    • Prophylaxis of clotting during hemodialysis sessions
      This medicine is used for the prevention of clot formation in the extracorporeal circulation during hemodialysis sessions that last more than 1 hour
    Nadroparin (Ca) is contraindicated in conditions like Diabetic retinopathy, Severe uncontrolled hypertension, Hypersensitivity to any component of product.

    Major & minor side effects for Nadroparin

    • Injection site redness, bruising, or sores
    • Unusual bleeding or bruising
    • Dark red spots in the mouth
    • Bloody or coffee colored vomit
    • Black or tarry stools
    • Excessive menstrual bleeding
    • Dizziness and lightheadedness
    • Swelling of eyelids, face, lips, tongue
    • Difficulty in breathing
    • Difficulty in swallowing
    • Back pain
    • Muscle weakness
    • Fever
    • Burning or tingling sensation of skin

    Drug should not be given to Paediatrics, patients suffering from Kidney dysfunction, and patients suffering from Liver Malfunction.

    Patients with recent or anticipated neuraxial anesthesia (epidural or spinal anesthesia) are at risk of spinal or epidural hematoma and subsequent paralysis. Patient should be closely monitored for sighns or symptoms of bleeding.Should be use with caution in patients with severe hepatic or renal disease. Safety and efficacy in pediatric patients have not been established. Should not be used interchangeably (unit for unit) with heparin or any other low molecular weight heparins.

    Pregnancy

    This medicine is recommended for use in pregnant women only when absolutely necessary and the potential benefits outweigh the risks involved.

    Breast-feeding

    This medicine is not recommended for use in breastfeeding women since the safety and efficacy are not clinically established. Replacement with a suitable alternative should be done under your doctor’s supervision.

    Adult

    85 units-85 (85)-12 hourly-S/C-For angina & Treatment of thromboembolism For angina 6 days thromboembolism 10 days

    2850 units-2800 (2850)-12 hourly-S/C-For 7 days. For haediallysis & for prophylaxis of venous thromboembolism

    Pediatric

    Not recommended for this age group

    Neonatal

    No data regarding the neonatal dosage details of Nadroparin (Ca) is available

    Nadroparin Calcium

    Injections

    • 9500 IU