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    DEA Class; (Herb/Suppl)

    Common Brand Names; Cannabis, Ganja, Hash, Hashish, Hemp, Mary Jane, Pot, Reefer, Weed

    • Analgesics, Herbals

    Tetrahydrocannabinol (THC), a component of marijuana, acts both centrally and peripherally on endogenous cannabinoid receptors; activation of cannabinoid receptors affects serotonin release, increases catecholamines, inhibits parasympathetic activity, and inhibits prostaglandin biosynthesis

    Decrease intraocular pressure, analgesia, antiemetic effects, appetite stimulant

    Indicated for

    • Analgesia, Antiemetic, Appetite Stimulant, Glaucoma
    • Treatment of HIV-associated wasting syndrome
    • Hepatocellular Carcinoma (Orphan)


    Coadministration with dronabinol (Cannabis derivative)

    • Tolerance
    • Psychological or physical dependence
    • Withdrawal symptoms
    • Altered sensorium
    • Dizziness
    • Somnolence
    • Fatigue
    • Reduced coordination
    • Cognitive impairment
    • Impaired balance
    • Euphoria
    • Paranoia
    • Hallucinations
    • Mood alterations
    • Panic
    • Anxiety
    • Hypotension
    • Hypertension
    • Tachycardia
    • Flushing
    • Syncope
    • Xerostomia
    • Nausea
    • Vomiting
    • Dysgeusia
    • Tooth discoloration
    • Anorexia
    • Increased appetite
    • Oral candidiasis
    • Diarrhea
    • Constipation
    • Urinary retention
    • Skin rash
    • Dry eyes
    • Blurred vision
    • Allergy
    • Cough
    • Pharyngitis

    History of substance abuse or mental illness

    Hepatic disease

    Cardiovascular disease

    Seizure disorders

    Nonpharmaceutical preparations contaminated with the fungus which may be hazardous to patients with compromised immune systems

    Geriatric patients

    Operating machinery or driving

    FDA pregnancy category not available; insufficient data regarding safety to fetus, avoid use

    THC found in Marijuana is reported to be concentrated and secreted into breast milk

    Analgesia, Antiemetic, Appetite Stimulant, Glaucoma

    Dosing of marijuana preparations is highly dependent on a variety of factors (eg, growing and harvesting conditions, plant parts isolated)

    No standard guidelines exist for dosage ranges


    • Tincture: 5-15 drops or 1-3 drops of fluid extract


    • 1-3 grains (65-195mg) cannabis for smoking
    • Potency highly variable
    • Drug deteriorates rapidly