Maltitol

Synonyms:Amalty; C*PharmMaltidex; E965; hydrogenated maltose; Malbit; Maltisorb; Maltit; D-maltitol; maltitolum.

Description: Maltitol occurs as a white, odorless, sweet, anhydrous crystalline powder. It is a disaccharide consisting of one glucose unit linked with one sorbitol unit via an a-(1!4) bond. The crystal structure is orthorhombic.

Chemical Name: 4-O-a-D-Glucopyranosyl-D-glucitol

Coating agent; diluent; granulation aid; sweetening agent.

• Maltitol is widely used in the pharmaceutical industry in the formulation of oral dosage forms.

• It is a noncariogenic bulk sweetener, approximately as sweet as sucrose, well adapted as a diluent for different oral dosage forms, wet granulation, and sugarfree hard coating

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Maltitol is used in oral pharmaceutical formulations, confectionery, and food products, and is considered to be noncariogenic. It is generally regarded as a nontoxic, nonallergenic, and nonirritant material. Digestion of maltitol follows two different metabolic pathways: absorption in the small intestine and fermentation in the large intestine (colon). These two metabolic pathways must thus be considered when evaluating the energy value.

Observe normal precautions appropriate to circumstances and quantity of material handled. Eye protection and gloves are recommended.

Sorbitol.