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    Synonyms: a-Aminoisocaproic acid; L-a-aminoisocaproic acid; 2-amino-4- methylpentanoic acid; 2-amino-4-methylvaleric acid; a-amino-gmethylvaleric acid; 1,2-amino-4-methylvaleric acid; D L-leucine; Lleucine; leu; leucinum; 4-methylnorvaline.

    Description: Leucine occurs as a white or almost off-white crystalline powder or shiny flakes

    Chemical Name: L-Leucine

    Antiadherent; flavoring agent; lubricant.

    • Leucine is used in pharmaceutical formulations as a flavoring agent.

    • It has been used experimentally as an antiadherent to improve the deagglomeration of disodium cromoglycate microL Leucine 387 particles and other compounds in inhalation preparations; and as a tablet lubricant.

    • Leucine copolymers have been shown to successfully produce stable drug nanocrystals in water.

    Leucine is incompatible with strong oxidizing agents.

    Leucine is an essential amino acid and is consumed as part of a normal diet. It is generally regarded as a nontoxic and nonirritant material. It is moderately toxic by the subcutaneous route.

    Observe normal precautions appropriate to the circumstances and quantity of the material handled.