General Description
Synonyms: a-Aminoisocaproic acid; L-a-aminoisocaproic acid; 2-amino-4- methylpentanoic acid; 2-amino-4-methylvaleric acid; a-amino-gmethylvaleric acid; 1,2-amino-4-methylvaleric acid; D L-leucine; Lleucine; leu; leucinum; 4-methylnorvaline.
Description: Leucine occurs as a white or almost off-white crystalline powder or shiny flakes
Chemical Name: L-Leucine
Uses
Leucine is used in pharmaceutical formulations as a flavoring agent.
It has been used experimentally as an antiadherent to improve the deagglomeration of disodium cromoglycate microL Leucine 387 particles and other compounds in inhalation preparations; and as a tablet lubricant.
Leucine copolymers have been shown to successfully produce stable drug nanocrystals in water.
Incompatibilities
Leucine is incompatible with strong oxidizing agents.
Safety
Leucine is an essential amino acid and is consumed as part of a normal diet. It is generally regarded as a nontoxic and nonirritant material. It is moderately toxic by the subcutaneous route.
Handling Precautions
Observe normal precautions appropriate to the circumstances and quantity of the material handled.
Related Substances
DL-Leucine