General Description
Synonyms: C*PharmIsoMaltidex; E953; galenIQ; hydrogenated isomaltulose; hydrogenated palatinose; IsoMaltidex 16500; isomaltum; Palatinit.
Description: Isomalt is a sugar alcohol (polyol) that occurs as a white or almost white powder or granular or crystalline substance. It has a pleasant sugarlike taste with a mild sweetness approximately 50–60% of that of sucrose.
Chemical Name: Isomalt
Functions
Coating agent; granulation aid; medicated confectionary base; sweetening agent; tablet and capsule diluent
Uses
Isomalt is a noncariogenic excipient used in a variety of pharmaceutical preparations including tablets or capsules, coatings, sachets, and suspensions, and in effervescent tablets.
It can also be used in direct compression and wet granulation.
In buccal applications such as chewable tablets it is commonly used because of its negligible negative heat of solution, mild sweetness, and ‘mouth feel’.
It is also used widely in lozenges, sugar-free chewing gum, and hard-boiled candies, and as a sweetening agent in confectionery for diabetics
Safety
Isomalt is used in oral pharmaceutical formulations, confectionery, and food products. It is generally regarded as a nontoxic, nonallergenic, and nonirritant material.
Handling Precautions
Observe normal precautions appropriate to the circumstances and quantity of material handled. Eye protection, gloves, and a dust mask or respirator are recommended.