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    DEA Class; Rx

    Common Brand Names; Yodoxin

    • Antiparasitic Agents

    Acts primarily in intestinal lumen; mechanism unknown

    Indicated for Intestinal Amebiasis

    Hypersensitivity to 8-hydroxyquinolones or iodoquinol

    Iodine sensitivity

    Pre-existing optic neuropathy

    Hepatic damage

    • Headache
    • Chills
    • Agitation
    • Diarrhea
    • Rash
    • Fever
    • Urticaria
    • Pruritus
    • Thyroid gland enlargement
    • Retrograde amnesia
    • Nausea
    • Vomiting
    • Peripheral neuropathy
    • Optic neuritis
    • Stomach pain
    • Weakness
    • Visual impairment
    • Optic atrophy
    • Abdominal cramps
    • Itching of rectal area

    Caution in thyroid disease

    Interferes with thyroid tests for up to 6 months after discontiunation

    Do not repeat course before 2-3 wk

    Not effective in amebic hepatitis or liver abscess

    Avoid long term thearpy (associated with optic neuritis and optic atrophy)

    Pregnancy Category: C

    Lactation: unknown


    650 mg PO PC q8hr for 20 days; not to exceed 2 g/day


    30-40 mg/kg/day divided PO PC q8hr PO for 20 days; not to exceed 1.95 g/day  


    Not the drug of choice (may cause optic nerve damage); use only if other therapy is contraidicated or failed



    • 210mg
    • 650mg