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Guaifenesin/Pseudoephedrine

    Brands

    DEA Class; Rx

    Common Brand Names; Mucinex D, Guaifenex PSE, Refenesen Plus, Sinutab Non-Drying, Congestac

    • Cough/Cold, Other Combos; 
    • Decongestant/Expectorant Combos

    Oral expectorant and sympathomimetic decongestant combination
    Primarily used for the temporary relief of congestion associated with the common cold or other upper respiratory conditions
    Used in adults and pediatric patients 6 years and older

    Indicated for the treatment of cough and nasal congestion, including relief of eustachian tube congestion, associated with the common cold, sinusitis, or other upper respiratory conditions.

    Contraindicated in documented hypersensitivity to either drug or components

    Within 14 days of MAO inhibitor therapy

    • Arrhythmia
    • Palpitations
    • Convulsion
    • Dizziness
    • Drowsiness
    • Excitability
    • Headache
    • Tremor
    • Weakness
    • Nausea
    • Vomiting

    Use caution in high blood pressure, thyroid disease

    Caution in cardiovascular disease, diabetes mellitus, prostatic hypertrophy, and increased intraocular pressure when taking pseudoephedrine

    Guaifenesin is not for administration in persistent cough associated with chronic bronchitis, smoking, asthma, or accompanied by excessive secretions

    Discontinue use if you experience dizziness, insomnia, nervousness, experience persistent headache, symptoms do not improve within 7 days, or occur with a fever

    Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

    NOTE: Do not exceed recommended dosage limits for the specific product prescribed; the following are general guidelines:

    Adults

    Guaifenesin 2400 mg/day PO; pseudoephedrine 240 mg/day PO.

    Geriatric

    Guaifenesin 2400 mg/day PO; pseudoephedrine 240 mg/day PO.

    Adolescents

    Guaifenesin 2400 mg/day PO; pseudoephedrine 240 mg/day PO.

    Children

    12 years: Guaifenesin 2400 mg/day PO; pseudoephedrine 240 mg/day PO.
    6 to 11 years: Guaifenesin 1200 mg/day PO; pseudoephedrine 120 mg/day PO.
    Less than 5 years: Safety and efficacy have not been established.

    Infants

    Safety and efficacy have not been established.

    Guaifenesin/Pseudoephedrine

    caplet

    • 400mg/60mg

    tablet

    • 400mg/20mg
    • 400mg/30mg
    • 400mg/40mg
    • 400mg/60mg

    tablet extended release

    • 1200mg/120mg
    • 600mg/60mg