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Flurazepam

    Brands

    DEA Class;  Rx

    Common Brand Names; Dalmane

    • Sedative/Hypnotics

    Oral benzodiazepine with a relatively long half life.
    Used as a hypnotic agent in the short-term management of insomnia.
    Likely to cause residual daytime effects vs. other shorter-acting benzodiazepines.

    Indicated for the short-term treatment of insomnia characterized by difficulty in falling asleep, frequent nocturnal awakenings, and/or early morning awakenings.

    For the short-term treatment of anxiety.

    Documented hypersensitivity

    Acute alcohol intoxication

    Myasthenia gravis (allowable in limited circumstances)

    Narrow angle glaucoma (questionable)

    Severe respiratory depression

    Depressed neuroses, psychotic reactions

    IV use in shock, coma, depressed respiration, patients who recently received other respiratory depressants

    Lactation

    Common

    • Ataxia

    • Dizziness

    • Drowsiness

    • Lethargy

    • Light-headedness

    Less Common

    • Chest pain, palpitations

    • Headache, irritability, nervousness, weakness

    • GI complaints

    • Myalgia

    • GU complaints

    Rare

    • Elevations of AST, ALT, bilirubin (T&D), alk phos

    Use caution in COPD, sleep apnea, renal/hepatic disease, open-angle glaucoma (questionable), depression, suicide ideation

    May impair ability to perform hazardous tasks

    Use caution in patients with history of drug abuse or acute alcoholism; tolerance, psychological and physical dependence may occur with prolonged use

    Pregnancy Category: X

    Lactation: Excretion in milk unknown; not recommended

    Adults

    30 mg/day PO at bedtime.

    Elderly

    15 mg/day PO at bedtime.

    Adolescents

     >= 15 years: 30 mg/day PO at bedtime.
     < 15 years: Safety and efficacy have not been established.

    Children

    Safety and efficacy have not been established.

    Flurazepam hydrochloride

    capsule: Schedule IV

    • 15mg
    • 30mg