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Ephedrine/Guaifenesin

    Brands

    DEA Class;  Rx

    Common Brand Names; Primatene Tablets, Bronkaid Dual Action Formula

    • Decongestant/Expectorant Combos

    Ephedrine: Alpha, beta-1, and beta-2 receptor agonist

    Guaifenesin: Expectorant; reduces viscosity of mucus by increasing effective respiratory tract hydration

    Indicated for temporary relief of mild symptoms of intermittent asthma including wheezing, tightness of chest, shortness of breath ephedrine

    Never diagnosed with asthma

    Within 2 weeks of taking MAOI

    Taking certain drugs for depression, psychiatric, or emotional conditions, or Parkinson’s disease

    Hypersensitivity to drug or excipients

    • Hypertension
    • Tachycardia
    • Emotional disturbance
    • Headache
    • Insomnia
    • Nervousness
    • Seizure
    • Hypersensitivity reaction
    • Tremor
    • Cough
    • Exacerbation of asthma
    • Productive cough

    This product will not provide quick relief from asthma symptoms, as would an inhaled bronchodilator

    Ask a doctor or pharmacist before use if taking prescription drugs for asthma, obesity, weight control, depression, or psychiatric or emotional conditions or if taking any drug that contains phenylephrine, ephedrine, or caffeine, including for allergy, cough-cold, or pain

    May cause hypertension or tachycardia; serious cardiovascular events (eg, MI, stroke, arrhythmias, including death) reported with use of dietary supplements containing ephedrine; risk of heart attack or stroke may increase with history of high blood pressure or heart disease, or if taking more frequently or taking a higher dose than recommended

    If you have been previously hospitalized for asthma, other prescription drugs for asthma should be used as directed by your physician

    Avoid foods or beverages that contain caffeine and avoid dietary supplements containing ingredients reported or claimed to have a stimulant effect

    Caution with heart disease, hypertension, diabetes, thyroid disease, seizures, narrow angle glaucoma, history of psychiatric or emotional condition, prostatic hypertrophy, productive cough, cough that lasts or is chronic (eg, owing to smoking, asthma, chronic bronchitis, emphysema)

    Discontinue use and see a physician if asthma is getting worse, have difficulty sleeping, experience rapid heartbeat, experience tremors, nervousness, or seizure

    Limited human data have not shown fetal harm with temporary oral use; if pregnant, ask a healthcare professional before use

    Ephedrine: Unknown if distributed in human breast milk

    Guaifenesin: Unknown if distributed in human breast milk

    Adults

    12.5-25 mg/guaifenesin 200-400 mg PO q4hr PRN

    Not to exceed ephedrine 150 mg/guaifenesin 2400 mg per 24 hr

    Pediatric

    <12 years: Safety and efficacy not established

    ≥12 years: 12.5-25 mg/guaifenesin 200-400 mg PO q4hr PRN

    Not to exceed ephedrine 150 mg/guaifenesin 2400 mg per 24 hr

    ephedrine/guaifenesin

    tablet

    • 12.5mg/200mg (Primatene Tablets)
    • 25mg/400mg (Bronkaid Dual Action Formula)