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Enoxacin

    DEA Class;  Rx

    Common Brand Names; Penetrex

    • Quinolones and fluoroquinolones

    Enoxacin is an antibiotic in a class of drugs called fluoroquinolones. It fights bacteria in the body.

    Enoxacin is used to treat various bacterial infections, such as gonorrhea and urinary tract infections.

    For the treatment of adults (≥18 years of age) with the following infections caused by susceptible strains of the designated microorganisms: (1) uncomplicated urethral or cervical gonorrhea due to Neisseria gonorrhoeae, (2) uncomplicated urinary tract infections (cystitis) due to Escherichia coliStaphylococcus epidermidis, or Staphylococcus saprophyticus, and (3) complicated urinary tract infections due to Escherichia coliKlebsiella pneumoniaeProteus mirabilisPseudomonas aeruginosaStaphylococcus epidermidis, or Enterobacter cloacae.

    Penetrex (enoxacin) is contraindicated in persons with a history of hypersensitivity, tendinitis, or tendon rupture associated with the use of enoxacin or any member of the quinolone group of antimicrobial agents.

    • an allergic reaction (difficulty breathing; closing of the throat; swelling of the lips, tongue, or face; or hives);

    • seizures;

    • confusion or hallucinations;

    • liver damage (yellowing of the skin or eyes, nausea, abdominal pain or discomfort, unusual bleeding or bruising, severe fatigue); or

    • muscle or joint pain.

    If you experience any of the following less serious side effects, continue taking enoxacin and talk to your doctor:

    • nausea, vomiting, or diarrhea;

    • headache, lightheadedness, or drowsiness;

    • ringing in your ears; or

    • increased sensitivity of the skin to sunlight.

    Pregnancy Category: C

    Lactation: –

    Usual Adult Dose for Gonococcal Infection — Uncomplicated:

    400 mg orally one time.

    Usual Adult Dose for Urinary Tract Infection:

    Uncomplicated: 200 mg orally every 12 hours for 7 days.
    Complicated: 400 mg orally every 12 hours for 14 days.

    Usual Adult Dose for Prostatitis:

    400 mg orally every 12 hours for 14 to 30 days.

    Usual Adult Dose for Pyelonephritis:

    400 mg orally every 12 hours for 14 days.

    Usual Adult Dose for Epididymitis — Non-Specific:

    200 mg orally every 12 hours for 14 days.

     

    Enoxacin 

    Tablet

    • 200mg
    • 400mg