Ticlopidine Uses/Indications Dosage Side effects- Drugsdose

Classes

DEA Class; Discontinued

Common Brand Names; Ticlid

Antiplatelet Agents, Cardiovascular;
Antiplatelet Agents, Hematologic

Oral platelet-aggregation inhibitor; associated with a risk of life-threatening blood dyscrasias; should be reserved for patients who are intolerant or allergic to aspirin therapy or who have failed aspirin therapy.

Indications

Indicated for arterial thromboembolism prophylaxis (e.g., stroke prophylaxis) to reduce the risk of sustaining an initial (fatal or nonfatal) thrombotic stroke after a transient ischemic attack (TIA) or to reduce the risk of recurrent thrombotic stroke in patients who have sustained a completed thrombotic stroke.

For subacute coronary thrombosis prophylaxis (i.e., abrupt closure) in combination with aspirin in recipients of a coronary artery stent following percutaneous coronary intervention (PCI).

For the treatment of acute myocardial infarction.

For the treatment of unstable angina as an alternative to aspirin.

For the treatment of intermittent claudication associated with peripheral vascular disease (PVD).

Contraindications

Documented hypersensitivity

Neutropenia, thrombocytopenia, hemostatic disorder or active bleeding (GI bleed, ICH), severe hepatic impairment, history of either thrombotic thrombocytopenic purpura (TTP) or aplastic anemia

Current use of other anticoagulant drugs