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Rimantadine

    Brands

    DEA Class; Rx

    Common Brand Names; Flumadine

    • Antivirals, Influenza

    Oral antiviral agent
    Indicated for prophylaxis and treatment of seasonal influenza A virus infections in patients 17 years and older, and for prophylaxis only in children (1 to 16 years)
    CDC and IDSA recommend against use due to high resistance

    Indicated for the treatment of seasonal influenza A virus infection.

    For seasonal influenza prophylaxis for infections due to influenza A virus.

    Hypersensitivity to amantadine, rimantadine or any drug component

    • Dizziness (2%)
    • Nervousness (1-2%)
    • Fatigue (1%)
    • Headache (1%)
    • Insomnia (2%)
    • Difficulty in concentrating (<2%)
    • Anxiety (1%)
    • Anorexia (2%)
    • Weakness (1%)
    • Nausea (3%)
    • Vomiting (2%)
    • Xerostomia (2%)
    • Abdominal pain (1%)
    • Anorexia (2%)
    • Dyspnea
    • Agitation
    • Ataxia
    • Tachycardia
    • Tremor

    CDC advises against use for treatment or prophylaxis of influenza in the US during the 2008-09 influenza season

    Caution in patients with history of seizures; discontinue if seizures occur

    Avoid use in patients with psychosis (active or uncontrolled)

    Caution in renal impairment

    Pregnancy Category: C

    Lactation: enters breast milk

    Adults

    200 mg/day PO.

    Geriatric

    200 mg/day PO; 100 mg/day PO in elderly nursing home patients.

    Adolescents

    200 mg/day PO.

    Children

    10 to 12 years: 200 mg/day PO.
    1 to 9 years: 5 mg/kg/day PO or 150 mg/day PO, whichever is less.

    Infants

    Safety and efficacy have not been established.

    Neonates

    Safety and efficacy have not been established.

    Rimantadine

    syrup

    • 50mg/5mL

    tablet

    • 100mg