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    DAE Class; Rx

    Common Brand Names; NO-SPA, NO-SPA FORTE

    • Antispasmodics

    Drotaverine is Cholinergic muscarinic antagonist. Drotaverine is used in smooth muscle spasm and stone formation

    Drotaverine is primarily indicated in conditions like Biliary spasm, Cholangitis, Cholecystitis, Cholecytolithiasis, Cystitis, Nephrolithiasis, Papilitis, Smooth muscle spasm, Stone formation, Ureterolithiasis, Urinary spasm, Urolithiasis, Vesical tenesmus.

    Drotaverine is contraindicated in conditions like Cardiac insufficiency, Renal insufficiency, Hepatic insufficiency, Av block of ii &iii degree.

    The severe or irreversible adverse effects of Drotaverine, which give rise to further complications include Porphyria.

    The symptomatic adverse reactions produced by Drotaverine are more or less tolerable and if they become severe, they can be treated symptomatically, these include Dizziness, Vertigo, Headache, Nausea, Vomiting, Palpitation, Constipation, Insomnia, Dry mouth, Hypotension, Dry mouth, dizziness.

    Fusidic acid is metabilized by the liver and excreted mainly through the bile, periodic liver function test should be carried out in the patient with liver dysfunction abnormalities in the biliary pathway or when the fusidic acid is given for prolonged periods, or when it is given in combination with other antibiotics which have similar excretion pathways, e.g. lincomycin and rifampicin.

    Drug should not be given to Pregnant Mothers, and patients suffering from Kidney dysfunction.

    Drug should not be given to Pregnant Mothers.

    Adult Dosage

    20 to 80 mg  /8 hourly /IV,IM

    120 to 240 mg /3 hourly / PO


    Inj: 40 mg, 40 mg/2ml,
    Tabs: 40 mg, 80 mg,