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Difluoroethane (HFC)

    Synonyms: Dymel 152a; ethylene fluoride; Genetron 152a; halocarbon 152a; HFC 152a; P-152a; propellant 152a; refrigerant 152a; Solkane 152a

    Description:Difluoroethane is a liquefied gas and exists as a liquid at room temperature when contained under its own vapor pressure, or as a gas when exposed to room temperature and atmospheric pressure. The liquid is practically odorless and colorless. Difluoroethane is noncorrosive and nonirritating.

    Chemical Name: 1,1-Difluoroethane

    • Difluoroethane, a hydrofluorocarbon (HFC), is an aerosol propellant used in topical pharmaceutical formulations.

    • Difluoroethane may be used as a vehicle for dispersions and emulsions. Since difluoroethane does not contain chlorine, there are no environmental controls on the use of this material as a propellant, since it does not deplete the ozone layer and is not a greenhouse gas.

    Compatible with the usual ingredients used in the formulation of pharmaceutical aerosols.

    Difluoroethane may be used as an aerosol propellant in topical pharmaceutical formulations. It is generally regarded as an essentially nontoxic and nonirritant material.

    Difluoroethane is usually encountered as a liquefied gas and appropriate precautions for handling such materials should be taken. Eye protection, gloves, and protective clothing are recommended. Difluoroethane should be handled in a well-ventilated environment. Fluorocarbon vapors are heavier than air and do not support life; therefore, when cleaning large tanks that have contained these propellants, adequate provision for oxygen supply in the tanks must be made in order to protect workers cleaning the tanks