Classes
DAE Class; Rx
Common Brand Names;
- Antispasmodics
Description
Difemerine (HCl) is antimuscarinic agent. Difemerine (HCl) is used in the symptomatic treatment of visceral spasms.
Indications
- Difemerine (HCl) is primarily indicated in conditions like Spasm.
Contraindications
Adverse Effects
No data regarding the side effects
Warnings
Difemerine should be used with caution in patients with active tuberculosis infection of respiratory tract or in untreated fungal, bacterial or systemic viral infections. Corticosteroids should only be used systemically with great caution in the presence of congestive heart failure (CHF), recent myocardial infraction(MI), hypertension, diabetes mellitus, epilepsy, glaucoma, hypothyroidism, liver failure, osteoprosis, peptic ulceration or renal impairment. Children may be at increase risk of some adverse effects, corticosteroid cause growth retardation and prolonged use is rarely justified. Passive immunization is recommended to non-immune patients who do come in contact with chicken-pox or measles. Live vaccine should not be given to patients receiving high dose systemic corticosteroid therapy nor for atleast 3 months afterwards, killed vaccine or toxoids may be given, although the response may be attenuated. During prolong treatment with corticosteroids, patients should be examined regularly, sodium intake may need to be reduced and calcium and potassium supplement may be necessary. Patient should carry cards given full details of their corticosteroid therapy. Avoid use during pregnancy. Use nasal steroids with caution until healing has occurred.
Pregnancy and Lactation
Pregnancy
Breast-feeding
Maximum Dosage
Adult
7.5 to 10 mg/day-8.8 (8.75)-24 hourly
Pediatric
No data regarding the Paedriatic dosage
Neonatal
No data regarding the neonatal dosage
How supplied
Difemerine (HCl)
Inj:
- 1 mg/ml
- 2 mg/ml