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Dextromethorphan/Menthol

    DEA Class; Rx

    Common Brand Names; Delsym Cough + Soothing Action

    • Antitussives, Non-narcotic Combos

    Dextromethorphan: Derivative of levorphanol; acts on cough center in medulla; decreases sensitivity of cough receptors and interrupts cough impulse transmission

    Menthol: Topical anesthetic that reversibly blocks nerve conduction near the application site, thereby producing temporary loss of sensation in a limited area

    Indicated for temporary relieve of sore throat, sore mouth, minor mouth irritation, and cough due to minor throat and bronchial irritation as with the common cold

    Hypersensitivity

    Concurrent use MOAIs or within 2 weeks after stopping MAOIs

    • Nausea
    • Vomiting
    • Constipation
    • Drowsiness
    • Dizziness
    • Sedation
    • Confusion
    • Nervousness

    Contact physician promptly if sore throat is severe, persists for >2 days, is accompanied or followed by fever, headache, rash, nausea or vomiting

    Ask physician before use for persistent or chronic cough associated with smoking, asthma, or emphysema

    Ask physician before use for cough accompanied by excessive phlegm

    Stop and contact physician or dentist if sore mouth does not improve in 7 days, irritation, pain or redness persists or worsens, swelling develops, or for a cough that last >7 days, reoccurs, or is accompanied by fever, rash, or persistent headache

    Pregnancy Category: C

    Lactation: Unknown if distributed in human breast milk

    Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

    2 lozenges dissolved in mouth, 1 immediately after the other, q4hr prn; not to exceed 12 lozenges/day

     

    Dextromethorphan/menthol

    lozenge

    • 5mg/5mg