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    DEA Class;  Rx

    Common Brand Names; Cyclogyl, AK-Pentolate

    • Cycloplegics/Mydriatics; 
    • Anticholinergic Agents, Ophthalmic

    Cycloplegic, mydriatic ophthalmic agent; ocular anticholinergic effects similar to atropine; used for cycloplegic refraction and diagnostic pupil dilation.

    For mydriasis induction and cycloplegia induction.

    Hypersensitivity to drug or components

    • Blurred vision
    • Burning sensation in eye
    • Light intolerance
    • Tachycardia
    • Conjunctivitis
    • Raised intraocular pressure
    • Hyperreactive response in Down’s syndrome children (atropine)
    • Drowsiness

    Remove contact lenses prior to administration and wait 15 min before reinserting

    The elderly may be predisposed to increased intraocular pressure

    Mydriatics may produce transient elevation of intraocular pressure; patients with untreated narrow-angle glaucoma or anatomically narrow angles may be susceptible to angle-closure following administration

    Dropper tip is not to touch any surface, as this may contaminate the solution

    A transient burning sensation may occur upon instillation

    Patients should be advised not to drive or engage in other hazardous activities while pupils are dilated

    Patients may experience sensitivity to light and should protect eyes in bright illumination during dilation

    Parents should be warned not to get this preparation in their child’s mouth and to wash their own hands and the child’s hands following administration

    Feeding intolerance may follow ophthalmic use of this product in infants; it is recommended that feeding be withheld for 4 hours after examination


    Animal reproduction studies have not been conducted; not known whether cyclopentolate can cause fetal harm when administered to a pregnant woman or can affect reproduction capacity; administer to a pregnant woman only if clearly needed


    Not known whether this drug is excreted in human milk; because many drugs are excreted in human milk, exercise caution when drug is administered to a nursing woman


    4 drops/eye/day.


    4 drops/eye/day.


    4 drops/eye/day 0.5% or 1% solution; 2 of the 4 drops may be with a 2% solution.


    4 drops/eye/day 0.5% or 1% solution; 2 of the 4 drops may be with a 2% solution.


    1 drop/eye/day 0.5% solution.


    1 drop/eye/day 0.5% solution.

    Cyclopentolate hydrochloride


    • 0.5%
    • 1%
    • 2%