Classes
DEA Class; (Herb/Suppl)
Common Brand Names; American cranberry, black cranberry, European cranberry, low cranberry, mossberry, Oxycoccus macrocarpus, trailing swamp cranberry, Vaccinium edule, Vaccinium erythrocarpum, vaccinium macrocarpon, Vaccinium occycoccus, Vaccinium vitis
- Urology, Herbals
Description
Pharmacology
Metabolism: N/A
Excretion: N/A
Mechanism of Action
Proanthocyanidins, other compounds prevent bacterial adherence to urothelium
Does not significantly decrease urine pH
Indications
Suggested Uses
UTI (prevention), urinary deodorizer for incontinent patients, type 2 diabetes, chronic fatigue syndrome, scurvy, pleurisy, as a diuretic, antiseptic, antipyretic, & cancer
Efficacy
Studies show significant reduction in the risk of recurrent UTI’s in the elderly, hospitalized patients, and pregnant women
No reliable evidence shows effectiveness for treating UTI
Urinary odor: Preliminary research shows there may be a reduction in urinary odor in patients receiving oral cranberry
Diabetes: Clinical studies show NO improvement in fasting blood glucose, HbA1c, fructosamine, triglyceride, HDL cholesterol, or LDL cholesterol levels in patients with type 2 diabetes
Contraindications
History of kidney stones
Adverse Effects
GI upset, diarrhea, kidney stones at high doses
Increased risk of cancer oxalate uroliths in predisposed patients
Warnings
Atrophic gastritis, hypochlorhydria
Potential interaction with warfarin & increased bleeding risk
Potential hypersensitivity
No evidence for efficacy in treatment
Pregnancy and Lactation
Pregnancy Category: avoid use
Lactation: avoid use
Maximum Dosage
Suggested Dosing
UTI, Prevention
Juice
- Cranberry juice cocktail (26% cranberry juice): 10-16 oz/day PO
- Cranberry juice: 15 mL BID PO
Capsule
- 400 mg BID PO
Urinary Deodorizer for Incontinent Patients
Cranberry juice cocktail
- 3-6 oz/day PO
How supplied
Cranberry
Sachet
- Each 5.6g sachet contains: Cranberry standardized powder extract…. 250mg