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Citric Acid/​Sodium Bicarbonate

    DEA Class; OTC

    Common Brand Names; Alka-Seltzer Heartburn Relief

    •  Antacids, Combos

    Citric acid: Antacid; forms sodium citrate which neutralizes stomach acid

    Sodium bicarbonate: Antacid; reacts with and neutralizes hydrochloric acid in the stomach

    Indicated for

    • Indigestion/Heartburn

    Sodium-restricted diet; 575 mg sodium/tablet

    Phenylketonurics; contains phenylalanine 5.6 mg/tablet

    Discontinue if taken maximum dosage for 2 weeks without relief

    Alters gastric pH and may interfere with absorption of some concurrent medications

    Pregnancy Category: C

    Lactation: Unknown whether distributed in breast milk

    Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

    Adult

    Dissolve 2 tablets in water and drink effervescent solution q4hr PRN

    Not to exceed 8 tablets/24 hr

    Pediatric

    <12 years: Safety and efficacy not established

    ≥12 years: Dissolve 2 tablets in water and drink effervescent solution q4hr PRN; not to exceed 8 tablets/24 hr

    Citric acid/sodium bicarbonate

    effervescent tablet

    • 1000mg/1940mg