Cellulose, Microcrystalline

Synonyms: Avicel PH; Cellets; Celex; cellulose gel; hellulosum microcristallinum; Celphere; Ceolus KG; crystalline cellulose; E460; Emcocel; Ethispheres; Fibrocel; MCC Sanaq; Pharmacel; Tabulose; Vivapur.

Description: Castor oil is a clear, almost colorless or pale yellow-colored viscous oil. It has a slight odor and a taste that is initially bland but afterwards slightly acrid.

Chemical Name:Cellulose

Adsorbent; suspending agent; tablet and capsule diluent; tablet disintegrant.

• Microcrystalline cellulose is widely used in pharmaceuticals, primarily as a binder/diluent in oral tablet and capsule formulations where it is used in both wet-granulation and direct-compression processes.

• In addition to its use as a binder/diluent, microcrystalline cellulose also has some lubricant and disintegrant properties that make it useful in tableting

• Microcrystalline cellulose is also used in cosmetics and food product

Microcrystalline cellulose is incompatible with strong oxidizing agents.

Microcrystalline cellulose is widely used in oral pharmaceutical formulations and food products and is generally regarded as a relatively nontoxic and nonirritant material. Microcrystalline cellulose is not absorbed systemically following oral administration and thus has little toxic potential. Consumption of large quantities of cellulose may have a laxative effect, although this is unlikely to be a problem when cellulose is used as an excipient in pharmaceutical formulations.

Observe normal precautions appropriate to the circumstances and quantity of material handled. Microcrystalline cellulose may be irritant to the eyes. Gloves, eye protection, and a dust mask are recommended.

Microcrystalline cellulose and carrageenan; microcrystalline cellulose and carboxymethylcellulose sodium; microcrystalline cellulose
and guar gum; powdered cellulose; silicified microcrystalline
cellulose.