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Carbidopa

    DEA Class;  Rx

    Common Brand Names; Lodosyn

    • Decarboxylase Inhibitors
    Decarboxylase inhibitor; prevents the peripheral conversion of levodopa to dopamine; more levodopa is then available for entry into the CNS in the treatment of Parkinson’s disease.

    For use with carbidopa-levodopa or with levodopa for Parkinson’s disease in patients for whom the dosage of carbidopa-levodopa combo provides less than adequate daily dosage of carbidopa, or in patients whose dosage requirement of carbidopa & levodopa necessitates separate titration of each entity

    Dosage dependent upon concurrent dose of carbidopa-levodopa or levodopa & patient’s specific needs

    no adverse reactions

    Adults

    200 mg/day PO taking into consideration carbidopa given alone and as part of the combination product.

    Elderly

    200 mg/day PO taking into consideration carbidopa given alone and as part of the combination product.

    Adolescents

    Safety and efficacy have not been established.

    Children

    Safety and efficacy have not been established.

    Carbidopa

    (tablet)

    • 25 mg