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Calcium Carbonate/Magnesium Hydroxide

    DEA Class;OTC

    Common Brand Names; Rolaids Extra Strength, Rolaids Regular Strength, Rolaids Regular Strength Liquid, Rolaids Ultra Strength, Rolaids Ultra Strength Liquid, Mylanta Supreme

    • Antacids, Combos

    Antacid: Neutralizes gastric secretions resulting in increased gastric pH

    Indicated to relieve heartburn, Indigestion

    Calcium carbonate

    • Anorexia
    • Constipation
    • Flatulence
    • Nausea
    • Vomiting
    • Hypercalcemia
    • Hypophosphatemia
    • Xerostomia
    • Acid rebound
    • Milk-alkali syndrome

    Magnesium hydroxide

    • Nausea
    • Constipation
    • Vomiting
    • Hypotension
    • Respiratory depression
    • Diarrhea
    • Abdominal crampin
    • Electrolyte imbalance
    • Muscle weakness
    • Parageusia








    Milk-alkali syndrome

    OTC use: Do not use the maximum dosage for >2 weeks; if symptoms persist, discontinue and contact a health care provider

    Magnesium hydroxide: Caution with neuromuscular disease (eg, myasthenia gravis) and renal insufficiency

    Calcium carbonate: Caution with a history of kidney stones; Ca oxalate formation may increase risk

    Pregnancy Category: C (calcium carbonate); B (magnesium hydroxide)

    Calcium and magnesium both cross the placenta; antacids containing calcium or magnesium are considered to be low risk during pregnancy, however avoid excessive use

    Supplement calcium and magnesium during pregnancy and lactation according to recommended daily allowance

    Lactation: Calcium and magnesium both appear in breast milk, use in nursing mothers appears to be safe

    Antacid: Typical dose 800-3,000 mg of calcium carbonate PO prn for symptoms

    Tablet: Chew 2-4 tabs PO prn

    Suspension: 10-20 mL PO prn

    Tablet and suspension strength varies; not to exceed ~7 g of calcium carbonate/day

    calcium carbonate/magnesium hydroxide

    chewable tablet

    • 550mg/110mg (Rolaids Regular Strength)
    • 675mg/135mg (Rolaids Extra Strength)
    • 1000mg/200mg (Rolaids Ultra Strength)

    oral suspension

    • (400mg/135mg)/5mL (Mylanta Supreme)
    • (550mg/110mg)/5mL (Rolaids Regular Strength Liquid)
    • (1000mg/200mg)/5mL (Rolaids Ultra Strength Liquid)