Classes
DAE Class; Rx
Common Brand Names; MIGRIL
Description
Caffeine / Cyclizine / Ergotamine is used for Migraine, Vascular headache, Nausea, Vomiting and dizziness associated with motion sickness, Nausea, Vomiting and dizziness associated with vertigo, Nausea, Vomiting and dizziness associated with post-operatively following administration of general anaesthesia and opioids, Bronchopulmonary dysplasia in premature infants, Apnea of prematurity, Orthostatic hypotension, Drowsiness and other conditions.
Indications
- Migraine
- Vascular headache
- Nausea, vomiting and dizziness associated with motion sickness
- Nausea, vomiting and dizziness associated with vertigo
- Nausea, vomiting and dizziness associated with post-operatively following administration of general anaesthesia and opioids
- Bronchopulmonary dysplasia in premature infants
- Apnea of prematurity
- Orthostatic hypotension
- Drowsiness
Contraindications
Allergy
Adverse Effects
- Ischemia
- Cyanosis
- Cold extremities
- Bradycardia
- Hypertension
- Nausea
- Vomiting
- Numbness
- Weakness
- Itching
- Drowsiness
- Dry mouth
- Headache
- Dermatitis
- Double vision
- Constipation
- Urinary retention
- Gastrointestinal disturbances
- Vasoconstriction
- Bone loss in postmenopausal women
- Anxiety disorders
Warnings
- Allergic reactions
- Do not administer with strong CYP3A4 inhibitors such as protease inhibitors and macrolides antibiotics
- Do not exceed the indicated dose
- Do not take more than 6 tablets for a single migraine attack
- Heart, kidney or liver problems
- Operating an automobile or machinery
- Pregnant, planning to get pregnant or breastfeeding
- Smoker
- Symptoms of overdose are vomiting, numbness, tingling, pain and cyanosis
- This medication can cause dependence
Pregnancy and Lactation
Please consult with your doctor for case-specific recommendations.
Maximum Dosage
Adult
Child Dose
How supplied
Caffeine / Cyclizine / Ergotamine