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Atracurium

    Brands

    DEA Class;  Rx

    Common Brand Names; Tracrium

    • Neuromuscular Blockers, Nondepolarizing

    Atracurium besylate is a non-depolarizing neuromuscular blocker used to facilitate endotracheal intubation and relax skeletal muscles during surgery.

    Atracurium is used for

    • Endotracheal Intubation, Mechanical Ventilation

    • Skeletal Muscle Relaxation During Surgery

    Hypersensitivity to drug or components; lack of ventilatory support, neuromuscular disease

    Skin flush (5%)

    Erythema (0.6%)

    Wheezing (0.2%)

    Increased bronchial secretions (0.2%)

    Pruritus (0.2%)

    Urticaria (0.1%)

    Wheals

    Erythema at injection site

    Bronchospasm (0.01%)

    Cyanosis (0.001%)

    Changes in heart rate (0.6-2.1%)

    Mean arterial pressure (1.9%)

    Additive/synergistic effects if administered with or following an opioid, sedative or anesthetic agent

    Closely monitor patients with bronchogenic carcinoma, dehydration, electrolyte imbalance, hypotension, hypothermia, myasthenia gravis, pulmonary disease

    Adequate ventilatory support mandatory, may experience resistance with >25% TBSA burns, may experience increased sensitivity with electrolyte disorders (hyperMg, hypoK, hypoCa)

    Pregnancy Category: C

    Lactation: excretion in milk unknown; use with caution

    Specific maximum dosage information is not available. Dosage must be individualized based on clinical response.

    Atracurium Besylate

    Injectable solution

    • 10mg/mL