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Amcinonide

    Brands

    DAE Class; Rx

    Common Brand Names; Cyclocort

    • Corticosteroids, Topical

    Topical high-potency corticosteroid
    Used to treat moderate to severe corticosteroid-responsive dermatoses and psoriasis

    Indicated for the treatment of Corticosteroid-Responsive Dermatoses.

    For the treatment of corticosteroid-responsive dermatoses, including atopic dermatitis, localized vitiligo, eczema, phimosis, lichen planus, and localized bullous pemphigoid.

    For the treatment of psoriasis.

    Underlying infection

    Hypersensitivity

    Use on groin, face, or axila

    Ophthalmic use

    Skin atrophy

    Striae

    Burning

    Dryness

    Irritation

    Itching

    Hypertrichosis

    Acneform lesions

    Secondary infection

    Pigmentation changes

    HPA suppression (with higher potency used >2 wk)

    Chronic therapy may interfere with growth and development in children

    Use med to very high potency for <2 wk to reduce local and systemic side effects

    Use low potency for chronic therapy

    Allergic contact dermatitis may occur

    Should not use occlusive dressings in presence of infection or weeping lesions

    Adrenal suppression may occur in younger patients or patients receiving high doses for prolonged periods

    Development of Kaposi’s sarcoma with prolonged use reported (discontinue therapy if it occurs)

    Avoid medium to very high potency on face, folds, groin because can increase steroid absorption

    Use lower potency for peds (ie, increase BSA/kg, therefore increase systemic absorption)

    Pregnancy Category: C

    Lactation: It is not known whether topical administration of topical corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk. Use with caution.

    Adults

    3 applications/day topically.

    Geriatric

    3 applications/day topically.

    Adolescents

    3 applications/day topically.

    Children

    3 applications/day topically.

    Infants

    Safe and effective use have not been established.

    Neonates

    Safe and effective use have not been established.

    Amcinonide 

    cream/ointment/lotion

    • 0.1%