Classes
DAE Class; Rx
Common Brand Names; Cyclocort
- Corticosteroids, Topical
Description
Topical high-potency corticosteroid
Used to treat moderate to severe corticosteroid-responsive dermatoses and psoriasis
Indications
Indicated for the treatment of Corticosteroid-Responsive Dermatoses.
For the treatment of corticosteroid-responsive dermatoses, including atopic dermatitis, localized vitiligo, eczema, phimosis, lichen planus, and localized bullous pemphigoid.
For the treatment of psoriasis.
Contraindications
Underlying infection
Hypersensitivity
Use on groin, face, or axila
Ophthalmic use
Adverse Effects
Skin atrophy
Striae
Burning
Dryness
Irritation
Itching
Hypertrichosis
Acneform lesions
Secondary infection
Pigmentation changes
HPA suppression (with higher potency used >2 wk)
Warnings
Chronic therapy may interfere with growth and development in children
Use med to very high potency for <2 wk to reduce local and systemic side effects
Use low potency for chronic therapy
Allergic contact dermatitis may occur
Should not use occlusive dressings in presence of infection or weeping lesions
Adrenal suppression may occur in younger patients or patients receiving high doses for prolonged periods
Development of Kaposi’s sarcoma with prolonged use reported (discontinue therapy if it occurs)
Avoid medium to very high potency on face, folds, groin because can increase steroid absorption
Use lower potency for peds (ie, increase BSA/kg, therefore increase systemic absorption)
Pregnancy and Lactation
Pregnancy Category: C
Lactation: It is not known whether topical administration of topical corticosteroids could result in sufficient systemic absorption to produce detectable quantities in human milk. Use with caution.
Maximum Dosage
Adults
3 applications/day topically.
Geriatric
3 applications/day topically.
Adolescents
3 applications/day topically.
Children
3 applications/day topically.
Infants
Safe and effective use have not been established.
Neonates
Safe and effective use have not been established.
How supplied
Amcinonide
cream/ointment/lotion
- 0.1%