Alitame

Synonyms: Aclame; L-aspartyl-D-alanine-N-(2,2,4,4-tetramethylthietan-3 yl)amide; 3-(L-aspartyl-D-alaninamido)-2,2,4,4-tetramethylthietane.

Description: Alitame is a white nonhygroscopic crystalline powder; odorless or having a slight characteristic odor.

Chemical Name: L-a-Aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide anhydrous

L-a-Aspartyl-N-(2,2,4,4-tetramethyl-3-thietanyl)-D-alaninamide
hydrate

Sweetening agent.

• Alitame is an intense sweetening agent developed in the early 1980s and is approximately 2000 times sweeter than sucrose. It has an insignificant energy contribution of 6 kJ (1.4 kcal) per gram of alitame.
• Alitame is currently primarily used in a wide range of foods and beverages at a maximum level of 40–300 mg/kg

Alitame may be incompatible with oxidizing and reducing substances or strong acids and bases.

Alitame is a relatively new intense sweetening agent used primarily in foods and confectionary. It is generally regarded as a relatively nontoxic and nonirritant material. Chronic animal studies in mice, rats, and dogs carried out for a minimum of 18 months at concentrations >100 mg/kg per day exhibited no toxic or carcinogenic effects. In people, no evidence of untoward effects were observed following ingestion of 15 mg/kg per day for two weeks.

Observe normal precautions appropriate to the circumstances and quantity of material handled. Eye protection and gloves are recommended. Alitame should be stored in tightly closed containers, and protected from exposure to direct sunlight and higher than normal room temperatures.

Acesulfame potassium; aspartame; saccharin; saccharin sodium; sodium cyclamate