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Alcaftadine

    DEA Class; OTC

    Common Brand Names; Lastacaft

    •  Antihistamines, Ophthalmic
     

    Topical ophthalmic H1-antagonist
    Used for the prevention of ocular pruritus associated with allergic conjunctivitis
    Once daily administration

    Indicated for prevention of itching associated with allergic conjunctivitis

    Hypersensitivity

    Ocular

    • Irritation

    • Burning

    • Stinging

    • Redness

    • Pruritus

    • Eye discharge

    • Eye swelling

    • Erythema of eyelid

    • Eyelid edema

    Nonocular

    • Nasopharyngitis

    • Headache

    • Influenza

    • Somnolence

    To minimize eye injury and contamination of dropper tip and solution, care should be taken not to touch eyelids or surrounding areas with dropper tip of bottle; keep bottle tightly closed when not in use

    Keep bottle tightly closed when not in use

    Do not use for contact lens–related irritation

    Remove contact lenses before instillation

    Use of mycophenolate mofetil (MMF) during pregnancy is associated with an increased risk of first-trimester pregnancy loss and an increased risk of multiple congenital malformations in multiple organ systems

    There are no data on presence of drug in human milk, or effects on milk production; there are limited data in the National Transplantation Pregnancy Registry on effects of mycophenolate on a breastfed child; studies in rats treated with MMF have shown mycophenolic acid (MPA) to be present in milk

    Adults

    1 drop/day ophthalmic solution in each eye.

    Geriatric

    1 drop/day ophthalmic solution in each eye.

    Adolescents

    1 drop/day ophthalmic solution in each eye.

    Children

    >= 2 years: 1 drop/day ophthalmic solution in each eye.
    < 2 years: Safety and efficacy have not been established.

    Infants

    Safety and efficacy have not been established.

    Neonates

    Safety and efficacy have not been established.

    Alcaftadine

    ophthalmic solution

    • 0.25%