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Senna/Docusate

    Brands

    DEA Class; OTC

    Common Brand Names; PeriColace, Senna Plus, Senna-S, Senokot-S

    • Laxatives, Stimulant

    Senna: intestinal irritant/stimulant

    Docusate: surfactant laxative/stool softener

    Indicated for treatment of Constipation

    Hypersensitivity

    GI obstruction or perforation

    Ulcerative colitis

    Symptoms of appendicitis or acute surgical abdomen

    Fecal impaction

    Concurrent use of mineral oil

    GI bleeding

    Rectal bleeding

    • Abdominal cramping
    • Diarrhea
    • Nausea/vomiting
    • Yellow-brown urine discoloration

    Finger clubbing (long-term use)

    Not for use as over the counter in patients experiencing abdominal pain, vomiting, nausea, sudden change in bowel movement that last > 2 weeks

    Not recommended for use >1 week or children < 2 years

    Pregnancy category: C (senna); B psyllium

    Lactation: Use caution

    Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

    Constipation

    2-4 tablets PO qDay; may increase to 4 tab q12hr

    Senna/docusate

    tablet

    • 8.6mg/50mg