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Magnesium Gluconate

    Brands

    DEA Class; OTC

    Common Brand Names; Mag-G, Magonate, Magtrate

    • Electrolytes

    Cofactor for many enzymatic pathways involved in phosphate transfer reactions that use ATP and other nucleotides as substrates (eg, oxidative phosphorylation, oxygen radical reduction)

    Indicated as a Dietary Supplement

    Hypersensitivity

    Hypermagnesemia

    Diarrhea

    Use caution in severe renal impairment

    Use extreme caution in patients with myasthenia gravis or other neuromuscular diseases

    May use for the treatment of constipation occasionally; prolonged use may result in serious side effects

    Patient should inform physician about prescription nonprescription medications being taken, especially other products with magnesium or tetracycline

    Inform physician about having or ever having kidney disease, intestinal disease, or stomach problems

    If pregnant or planning to become pregnant or breastfeeding, discuss these with physician

    Pregnancy Category: A; elemental magnesium dietary reference intake during pregnancy is 350-400 mg/day for adult women

    Lactation: Distributed in breast milk, elemental magnesium dietary reference intake for breast feeding women is 310-360 mg/day for adult women

    Adults

    RDA (Elemental Magnesium)

    Males: 400-420 mg PO qDay

    18-30 (Females)

    • 310 mg PO qDay
    • Pregnancy: 350 mg PO qDay
    • Lactation: 310 mg PO qDay

    >30 years (Females)

    • 320mg/day
    • Pregnant women: 360 mg/day
    • Lactating women: 320 mg/day

    Supplement

    Liquid: 5-10 mL initially (first day)

    Tablet: 2-4 tab initially (first day)

    Titrate to higher dose until stool softens and remains soft; reduce intake if loose stool

    Pediatric

    Magnesium Supplementation

    Dietary reference for PO intake of elemental magnesium varies in children according to age

    <6 months: 30 mg/day

    6-12 months: 75 mg/day

    1-3 years: 80 mg/day

    3-8 years: 130 mg/day

    8-13 years: 240 mg/day

    Adolescent boys 13-18 years: 410 mg/day

    Adolescent girls (13-18 years)
    • 360 mg/day
    • Pregnant: 400 mg/day
    • Lactating: 360 mg/day

    Magnesium gluconate