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Flucloxacillin (Floxacillin)

    Brands

    Floxacillin (Na) is also known as Flucloxacillin, Flucloxacillin, Flucloxacillin

    DAE Class; Rx

    Common Brand Names; Fluewell

    • Antibiotics, systemic

    Flucloxacillin is a penicillin-like antibiotic used for treating bacterial infections of the skin, bone, joint, heart, blood, lungs, throat, nose, ear, bladder, etc. caused by susceptible bacteria. It is also be used to prevent infections during major surgical procedures. This medicine is not recommended for treating common cold, flu or other viral infections since it is not effective in treating them.

    Bacterial infections

    This medicine is used for the treatment of bacterial infections of the skin, bone, joint, heart, blood, lungs, throat, nose, ear, bladder, etc. caused by susceptible bacteria. It is also be used to prevent infections during major surgical procedures.
    Can also be given in adjunctive therapy as an alternative drug of choice in Cardiothoracic surgery, Orthopaedic surgery.
    No data regarding the contra indications of Floxacillin (Na) is available.

    Major & minor side effects for Flucloxacillin

    • Stomach discomfort and pain
    • Skin Rash
    • Weakness and general discomfort
    • Fever
       
    • Diarrhea
    • Nausea and vomiting
    • Headache
       

    Before initiating therapy with flucloxacillin, careful inquiry should be made concerning previous hypersensitivity reactions to beta-lactams. Cross-sensitivity between penicillins and cephalosporins is well documented. Special caution is essential in the newborn because of the risk of hyperbilirubinemia. Studies have shown that, at high dose following parenteral administration, flucloxacillin can displace bilirubin from plasma protein binding sites, and may therefore predispose to kernicterus in a jaundiced baby. In addition, special caution is essential in the newborn because of the potential for high serum levels of flucloxacillin due to a reduced rate of renal excretion.

    Pregnancy

    This medicine is not recommended for use in pregnant women unless necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.

    Breast-feeding

    This medicine is not recommended for use in breastfeeding women unless necessary. The risks and benefits should be discussed with the doctor before taking/receiving this medicine.

    Maximum daily dose is 8 g per day.

    Usual adult (and children over 10 years of age) dosage:

    Oral: 250-500 mg three times a day.
    Usual children’s dosage:
    2-10 years: One-half adult dose.

    Under 2 years: One-quarter adult dose.
    Osteomyelitis, endocarditis: Up to 8 g daily in divided doses six- to eight-hourly.
    Surgical prophylaxis: 1 to 2 g IV at induction of anaesthesia followed by 500 mg six-hourly IV, IM, or orally at sixhourly intervals for up to 72 hours.

    Flucloxacillin, also known as floxacillin

    Injections

    • 1g
    • 500mg
    • 250mg

    Capsules

    • 500mg
    • 250mg