Naphazoline

DEA Class;  Rx, OTC

Common Brand Names; Privine, Naphcon, All Clear, All Clear AR, Bausch & Lomb Advanced Eye Relief Redness Instant Relief, Bausch & Lomb Advanced Eye Relief Redness Maximum Relief, Clear Eyes ACR Seasonal Relief, Clear Eyes for Dry Eyes Plus Redness Relief, Clear Eyes for Redness Relief, AKCon, Albalon, Rohto Cool

Ophthalmic vasoconstrictor used for redness and lubrication

CNS (anxiety, dizziness, tremor, etc)

Burning

Stinging

Sneezing

Dryness

Local irritation

Rebound congestion

Blurred vision

Mild transient stinging and/or irritation

Mydriasis

Increased or decreased intraocular pressure

Headache

Caution in HTN, hyperthyroidism, ocular injury, DM, open-angle glaucoma

Overuse may cause rebound congestion

Use with caution in patients with hypertension, cardiovascular abnormalities, diabetes mellitus, hyperthyroidism, infection, or injury

Stop use if vision changes, eye pain, or condition worsens

Concurrent use with MAO inhibitors may cause hypertensive crisis

Use in children, especially infants, may result in CNS depression leading to coma and marked reduction in body temperature

Advice patients to discontinue drug and consult physician if relief not obtained within 48 hours of therapy, if irritation, blurring or redness persists or increases, or if symptoms of systemic absorption occur, eg, dizziness, headache, nausea, decrease in body temperature, or drowsiness

To prevent contaminating dropper tip and solution, do not touch any surface, the eyelids or surrounding area with dropper tip of the bottle; if solution changes color or becomes cloudy, do not use

Pregnancy Category: C

Lactation: not known if excreted in breast milk

Adults

16 drops/day in each eye

Geriatric

16 drops/day in each eye

Adolescents

Safety and efficacy not established.

Children

Safety and efficacy not established.

Naphazoline Hydrochloride

Nasal spray

• 0.05% (20mL)

Ophthalmic solution

• OTC: 0.012%
• OTC: 0.02%
• 0.1%