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    DEA Class; OTC, Rx

    Common Brand Names; Allegra Anti-Itch Cooling Relief Cream, Allegra Anti-Itch Intensive Relief Cream

    • Anesthetics, Topical; 
    • Dermatologics, Other

    Diphenhydramine: Histamine H1-receptor antagonist; elicits topical anesthetic effects

    Allantoin: Skin protectant

    Temporarily relieves pain and itching associated with insect bites, minor skin irritations, sunburn, rashes, or minor burns, cuts, or scrapes


    Do not use more than directed

    Do not use large areas of the body

    Do not use with other diphenhydramine products, including oral products

    Do not use on deep or puncture wounds, animal bites, or serious burns

    Do not use on serious sunburn or broken, blistered or oozing skin

    Advise patient to contact physician if condition worsens or symptoms persist beyond 7 days

    Pregnancy Category: C

    Lactation: Unknown whether distributed in breast milk

    Pregnant or breastfeeding patients should seek advice of health professional before using OTC drugs

    Apply to affected area PRN; not to exceed 3-4 applications/day


    topical cream

    • 2%/0.5%